Biostimulators are a revolutionary class of injectables that go beyond traditional fillers by stimulating your body’s natural collagen production for long-lasting, gradual rejuvenation. Unlike hyaluronic acid fillers that simply add volume, biostimulators like Sculptra and Radiesse help improve skin texture, firmness, and elasticity from within—delivering results that look natural and continue to improve over time. Perfect for those seeking a subtle, refreshed appearance with long-term benefits.

Sculptra is a unique cosmetic injectable that helps aging skin rebuild and rejuvenate itself. Unlike traditional fillers that provide immediate volume, Sculptra works by gradually replacing lost collagen to restore your most youthful texture, tone, and contours.
By choosing Rise Rejuvenation Center, you are opting for a tailored treatment plan administered by experts who understand the delicate balance of facial structure. We use advanced Sculptra injection techniques to restore a youthful appearance that looks entirely natural, ensuring you look like the best version of yourself.

Increases natural collagen to restore deep facial volume.

Minimal; most patients return to regular activities immediately.

Long-lasting results, often persisting for two years or more.

Ideal for the cheeks, temples, jawline, and nasolabial folds.
Biostimulators are a specialized category of cosmetic injectables designed to stimulate collagen growth rather than just filling in lost volume. While hyaluronic acid fillers provide instant volume by "filling" a gap, a collagen-stimulator like Sculptra or Radiesse triggers a biological response in the areas where it is injected. This process improves overall skin quality and thickness, addressing the root causes of aging by rebuilding the body's natural collagen production, which diminishes over time.


Sculptra is an FDA-approved injectable that helps gradually replace lost collagen for results that can last up to two years. As a poly-L-lactic acid (PLLA) collagen stimulator, Sculptra helps restore the deep, underlying structure of the skin to diminish facial wrinkles. Sculptra works with your body within the deep dermis to help revitalize collagen production and help restore your skin’s inner structure and volume. As the Sculptra PLLA microparticles are absorbed, they help stimulate collagen production.

Radiesse is a dermal filler made up of calcium hydroxylapatite microspheres that is used to smooth the skin and add volume to areas like the face, neck, and chest. Radiesse adds initial volume after injection, but it continues working by stimulating collagen and elastin. The microspheres from Radiesse absorb over time, leaving your body's collagen in its place.

On the day of your Sculptra treatment, your Rise provider will first map out the treatment area to ensure optimal results. The Poly-L-lactic acid solution is injected deep into the dermis with a narrow needle or cannula. Most people find the procedure very tolerable, as the solution is often mixed with lidocaine for comfort. The actual treatment takes about 30–45 minutes. Immediately after the injections, the area may appear full due to the injectable's water content, but this will subside within a few days as the real work of collagen formation begins.

Sculptra is highly effective at treating concerns caused by lost volume and skin laxity, including:
Beyond the face, Sculptra is FDA-approved for restoring lost volume in the body. It is frequently used for buttocks augmentation (the "Sculptra BBL"), smoothing cellulite, and rejuvenating the skin on the chest, decolletage, and above the knees.
The primary benefits of Sculptra lie in its subtlety and longevity. Because it relies on natural collagen growth, your appearance improves over a few months, avoiding the "over-filled" look sometimes associated with other fillers. While traditional fillers may need to be refreshed every 6–12 months, Sculptra results can last up to two years. Sculptra doesn't just hide wrinkles; it helps maintain the skin’s structure by stimulating collagen production, leading to firmer, healthier-looking skin that glows from within.

You are likely an ideal candidate for Sculptra treatment if you notice signs of aging, such as sagging, hollowing, or deep facial wrinkles. Sculptra is perfect for those who want long-lasting results but prefer a gradual change. Sculptra should be avoided if you have a history of keloid scarring or are currently experiencing a skin infection at the injection site. During your consultation, your aesthetic specialist will discuss your medical history to ensure this is the right cosmetic treatment for you.

Recovery from a Sculptra treatment is straightforward, but good aftercare is key. You may experience minor swelling or bruising for a few days. The most important aftercare step is the "Rule of 5s": massage the treatment area for 5 minutes, 5 times a day, for 5 days. This ensures the poly-L-lactic acid particles are evenly distributed, preventing the formation of small bumps under the skin. You can resume regular activities almost immediately, though we recommend avoiding intense heat or exercise for 24 hours.

Because Sculptra is a collagen stimulator, improvements are not instant. You will notice a gradual change as your body produces more collagen over the next few months. Usually, a series of 2–3 sessions spaced about six weeks apart is recommended for optimal results.
Once natural collagen has been restored in the treatment area, the skin appears thicker, firmer, and more lifted. These results are long-lasting, frequently remaining visible for two years or more. By gradually replacing lost collagen, Sculptra provides a timeless, youthful appearance that evolves with you.

At Rise Rejuvenation Center, we pride ourselves on providing a white-glove experience and natural-looking outcomes for every patient. Our team understands that Sculptra requires an understanding of facial anatomy and an artistic eye for harmony and balance. We take the time to develop a tailored treatment plan that respects your unique features. When you choose us, you are choosing a partner dedicated to your natural beauty and long-term skin health. Schedule your personal consultation to get started today.
No, the particles will very gradually disappear, but the collagen produced could last for five or more years. The longevity of results may vary depending on factors like your metabolism and the amount of product used.
Sculptra is an FDA-approved injectable for many facial areas, such as the jawline, mid-lower face, neck region, and even body parts such as the buttocks, cellulite correction, and crepey skin that can be found above the knee caps.
Radiesse provides immediate volume and structure while also stimulating collagen over time, making it ideal for areas like the jawline, cheeks, and hands. Sculptra works gradually to restore lost volume by stimulating collagen production, with results that appear over several weeks and can last up to two years.
While most patients see significant improvements after one treatment, a series of 3 sessions is typically recommended to restore maximum volume and achieve optimal results.
Both types of injectables are FDA-approved and safe. Sculptra is made of poly-L-lactic acid, a biocompatible material used for decades in dissolvable stitches. Complications are rare when the treatment is performed by a trained healthcare provider.
No, and that is one of the benefits! Initially, you will see some swelling from the water in the injection, but the natural collagen production takes time. You will see your most refined treatment results after a few months.
Absolutely. Many patients combine Sculptra with Botox or HA dermal fillers to address different types of wrinkles and aging concerns simultaneously for a full-face rejuvenation.